Migraine is a neurological condition and it Is frequently characterized by intense and debilitating headaches. Other symptoms may include nausea, vomiting, difficulty in speaking, numbness or tingling, and sensitivity to light and sound. Most migraines last about 4 hours. If it could not be treated or doesn’t respond to treatment, it can last for as long as 72 hours up to a week. If you and anyone you know have migraines, you already know how painful and debilitating it is.
Migraine sufferers also tend to experience depression, anxiety, and sleep problems. The exact causes of Migraine are not known, but it may be caused by changes in the brainstem and its interactions with the trigeminal nerve, and the neurogenic inflammation. Among these, the endocannabinoid system (ES) has recently attracted considerable attention. Experimental and clinical data suggest a link between dysregulation of this signaling complex and migraine headache.
Imbalance in brain chemicals—including serotonin, which helps to regulate pain in your nervous system may also be involved. Researchers are still studying the role of serotonin in migraine, but serotonin levels in the brain drop during migraine. Migraine may be triggered by a variety of other factors like hormonal changes, foods, food additives, drinks like coffee, wine, and alcohol, stress, and changes in sleeping habits. Most migraineurs search for treatment, how to effectively manage and overcome that painful condition.
The link between Endocannabinoid and Migraine
Recent studies show that migraine headaches may be due to endocannabinoid deficiency and abnormal inflammatory response. Triggers (mentioned above) initiate a chemical reaction in the brain, one that (non-migraineurs) would normally stimulate the release of endogenous cannabinoids to restore balance. But migraineurs may not produce endogenous cannabinoids in the face of these triggers. Chronic migraine sufferers have an endocannabinoid deficiency. This leads to a cascade of pain-inducing signals within the brain, which causes dilation of blood vessels and an increase in pressure and swelling.
If you get migraines, you’ve likely looked for all kinds of treatments to ease your headache pain. Along with pain medication, migraine home remedies, and lifestyle changes. You might have considered CBD for migraines. Let’s deep dive into how CBD Help to Effectively Manage Migraine.
What Is Cannabidiol (CBD)
Cannabidiol is a chemical in the Cannabis sativa plant, also known as marijuana or hemp. Over 80 chemicals, known as cannabinoids, have been identified in the Cannabis sativa plant. While delta-9-tetrahydrocannabinol (THC) is the main psychoactive component of marijuana. THC produces high cannabidiol, which is also obtained from hemp and contains a very small amount of THC.
CBD is the most abundant cannabinoid found in full-spectrum hemp extracts. However, there are over 80 different cannabinoids, vitamins, minerals, and terpenes found in hemp. These components of hemp may increase the medicinal value of CBD and help to effectively alleviate migraines.
Role of the endocannabinoid system
The endocannabinoid system (ECS) is a complex cell-signaling system. The endocannabinoid system involves three core components: endocannabinoids, receptors, and enzymes. As part of our biological makeup, all of us are equipped with an endogenous cannabinoid system. The endogenous cannabinoid system regulates the production, it is responsible for breaking down cannabinoids and the uptake of cannabinoids. It is believed to promote bodily homeostasis by regulating a diverse array of physiological processes. It regulates body temperature, thirst, hunger, sleep, digestion, heart rate, pain, and much more.
The endogenous cannabinoid system is vast and complex and has only just begun to be explored. Two main types of cannabinoid receptors are :
CB1 receptors; which are located throughout the brain, central nervous system, connective tissues, and related organs; these are the primary receptor for THC, the notorious psychoactive compound in cannabis. It’s believed that CB1 receptors are the most densely populated receptor found in the human brain.
CB2 receptors; which are located throughout the peripheral nervous system, especially immune cells. CB2 receptors are critical for the regulation of the gastrointestinal system and the immune system. Its receptors do not produce the “high” associated with cannabis use.
Medicinal cannabis is used to properly align the body’s endocannabinoid system, often by supplementing cannabinoids derived from the cannabis plant. One can procure state well-being through bodily homeostasis, in which all physiological processes are balanced. The use of CBD and THC can fulfill endocannabinoid deficiencies, reduce inflammation and also reduce oxidative stress.
How to Use CBD Oil
It is suggested that patients who worked with a health care practitioner experienced in recommending CBD or medicinal cannabis. So that dosage and delivery methods can be developed and fine-tuned on an individual basis. Most discussions of treating pain with CBD suggest that finding the right dosage is critical. See how the right dosage is critical of CBD help to effectively manage migraine.
Always start with the micro dose to test sensitivity and go up as needed within the dosing range by body weight until symptoms subside. The micro to standard dose is usually recommended to treat migraines, but patients need to carefully monitor their condition and experiment to find the right formula.
A low dose is about 5 mg of CBD per day. Higher doses commonly used for chronic pain are 15 mg or 20 mg of CBD per day or twice per day, and even higher dosage in some cases. Most hemp extracts manufacturers recommend starting off with low doses and working up to higher doses to find the sweet spot.
CBD dosage adjustment.
You could start off at 5 mg per day and increase this dose by 5 mg every week until you find your desired dose. You may feel best with 5 mg per day, 15 mg per day, 25 mg per day, or 50 mg per day. Manufacturers and doctors need more surveys and researches to give a recommended dose.
CBD may ease the pain because it affects specific receptors in the brain. These receptors are part of the wider endocannabinoid system, which plays a role in pain and inflammation throughout the body.
CBD (Hemp) extract has the potential to stop migraines. The research suggests it can do this with the power of antioxidants, anti-inflammatories and help to reduce stress relief, improve sleep, and more. This is only the start of your quest for using CBD.
Scientific Studies on how CBD Help to Effectively Manage Migraine
The first migraine clinical trial for cannabis was published in May of 2016. In the study, 103 of 121 migraineurs reported a decrease in migraines. The study found that, on average, migraine-suffering patients who used medical marijuana saw their frequency of migraines drop significantly. While initial findings are encouraging with regards to CBD and migraine treatment, future research may shed more light on how migraines manifest and what CBD works to decrease the symptoms.
Although some research has shown that migraine sufferers report more relief from cannabis than they do from prescription medications. Clinical studies that focus specifically on the effect that CBD can have on migraine are yet to be conducted. However, a 2018 study found that CBD, a non-intoxicating constituent of cannabis, has several properties including acting as an anti-inflammatory, and anecdotal accounts of CBD oil, successfully being used for migraine show promising results.